Letrozole (Letrozole)

1. What is Letrozole used for?

Letrozole is used primarily for the treatment of **breast cancer** in postmenopausal women. It is classified as an **aromatase inhibitor** that works by lowering the levels of **estrogen** in the body, which helps slow or stop the growth of **hormone-receptor-positive breast cancer** cells. It is also used to treat **infertility** in women with polycystic ovary syndrome (**PCOS**) by stimulating ovulation.

2. How does Letrozole work?

Letrozole works by inhibiting the action of the enzyme **aromatase**, which is responsible for converting androgens into **estrogen**. By reducing the estrogen levels in the body, **Letrozole** helps to prevent the growth of estrogen-dependent breast cancer cells. In the context of **infertility**, it can promote ovulation by regulating hormonal balance.

3. How do I take Letrozole?

Letrozole is usually taken once a day, with or without food. The typical dosage for **breast cancer** treatment is **2.5 mg daily**, and for **infertility** treatment, it may vary depending on your doctor's prescription. It’s important to follow your doctor’s instructions precisely to achieve the best results.

4. What are the common side effects of Letrozole?

Common side effects of Letrozole include:

• Hot flashes
• Joint pain or stiffness
• Fatigue
• Headaches
• Nausea
• Bone thinning or **osteoporosis**

Most side effects are mild, but if you experience severe symptoms such as **severe bone pain**, **chest pain**, or **swelling in the legs**, contact your doctor immediately.

5. Can I use Letrozole with other medications?

Letrozole may interact with other medications, including those used to treat **breast cancer**, **high blood pressure**, and **diabetes**. Inform your healthcare provider about any other medicines you are taking, including **over-the-counter** drugs and **herbal supplements**, to avoid potential interactions.

6. Is Letrozole safe during pregnancy or breastfeeding?

Letrozole should not be used during pregnancy, as it can harm the unborn child. It is also not recommended for use while breastfeeding. Women taking Letrozole should use effective contraception to avoid pregnancy during treatment. If you are planning to become pregnant or are breastfeeding, consult your doctor before starting Letrozole.

7. How long will I need to take Letrozole?

The duration of treatment with Letrozole depends on the condition being treated. For **breast cancer**, the treatment duration is typically **5 years** or as recommended by your doctor. For **infertility treatment**, Letrozole is generally used for a few cycles, but your doctor will determine the appropriate length of treatment based on your response to the medication.

8. What should I do if I miss a dose of Letrozole?

If you miss a dose of Letrozole, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. **Do not take two doses at once** to make up for a missed dose.

9. Are there any precautions when using Letrozole?

Before using Letrozole, inform your doctor if you have a history of:

• Osteoporosis or **bone thinning**
• High cholesterol or **heart disease**
• Liver problems
• Kidney problems

Your doctor will monitor your condition while using Letrozole and may suggest appropriate screenings, such as bone density tests or liver function tests.

10. Where can I buy Letrozole?

Letrozole is available for purchase on our website or at authorized pharmacies. To check availability, view pricing, or find a nearby pharmacy, visit our Store Locator page.