Hydrea (Hydroxyurea)

1. What is Hydrea (Hydroxyurea) used for?

Hydrea (generic name **Hydroxyurea**) is primarily used in the treatment of certain types of **cancer** such as **leukemia** and **polycythemia vera**, and to manage **sickle cell anemia**. It works by interfering with the growth of cancer cells or by reducing the number of red blood cells produced in individuals with **polycythemia vera** or **sickle cell disease**. It can also be used to decrease the frequency of **pain crises** in **sickle cell anemia** patients.

2. How does Hydrea (Hydroxyurea) work?

Hydrea works by inhibiting **DNA synthesis**, which can slow or stop the growth of cancer cells and reduce the abnormal production of blood cells in conditions like **polycythemia vera** and **sickle cell anemia**. By interfering with **DNA replication**, it helps reduce the **pain crises** associated with sickle cell disease and prevent the uncontrolled growth of cancerous cells.

3. How should I take Hydrea (Hydroxyurea)?

Hydrea is typically taken as an oral tablet, usually once a day or as prescribed by your doctor. The dosage will depend on your specific medical condition, body weight, and overall response to the treatment. It is important to take the medication exactly as directed by your healthcare provider. Do not alter the dosage without consulting your doctor.

4. What are the common side effects of Hydrea (Hydroxyurea)?

Common side effects of Hydrea may include:

• Fatigue
• Loss of appetite
• Headache
• Nausea or vomiting
• Skin rash
• Hair loss (temporary)

Serious side effects can include a **decrease in blood cell count**, which may increase the risk of infections or bleeding. It is important to regularly monitor blood counts during treatment with **Hydrea**. If you experience any unusual or severe side effects, contact your healthcare provider immediately.

5. Can I take Hydrea (Hydroxyurea) with other medications?

Hydrea can interact with other medications, particularly those that affect the **bone marrow** or **immune system**, such as chemotherapy drugs. Always inform your doctor about any medications you are taking, including **prescription**, **over-the-counter**, and **herbal supplements**, to avoid potential drug interactions.

6. Is Hydrea (Hydroxyurea) safe during pregnancy or breastfeeding?

Hydrea can be harmful to an unborn baby and should generally be avoided during pregnancy unless the potential benefit justifies the risk. If you are pregnant, planning to become pregnant, or breastfeeding, discuss with your doctor whether this medication is right for you. It is also important to use **birth control** while taking **Hydrea** and for a period after treatment to prevent pregnancy.

7. How long will I need to take Hydrea (Hydroxyurea)?

Hydrea is typically used as a **long-term treatment** for conditions like **polycythemia vera**, **sickle cell anemia**, and certain cancers. The duration of treatment will depend on your condition and how you respond to the medication. Your doctor will regularly assess your progress and adjust the treatment as needed.

8. What should I do if I miss a dose of Hydrea (Hydroxyurea)?

If you miss a dose of **Hydrea**, take it as soon as you remember unless it is almost time for your next dose. Do not take **two doses** to make up for the missed dose. If you have any concerns or questions, contact your doctor for further instructions.

9. Are there any precautions when using Hydrea (Hydroxyurea)?

Before using **Hydrea**, inform your doctor if you have any of the following conditions:

• Bone marrow suppression or **low blood counts**
• Liver disease
• Kidney problems
• History of cancer or other serious health conditions

Your doctor may adjust the dose or monitor you more closely during treatment to avoid complications.

10. Where can I buy Hydrea (Hydroxyurea)?

Hydrea is available by prescription at most pharmacies. You can find more details on pricing and availability by visiting a local pharmacy or contacting your healthcare provider for more information.