Alpostin Prostaglandin E2 Injection

1. What is Alpostin (Prostaglandin E2) Injection used for?

Alpostin contains Prostaglandin E2 (PGE2) and is commonly used for inducing labor in pregnant women at term. It helps soften and dilate the cervix, facilitating uterine contractions for labor induction.

2. How does Prostaglandin E2 in Alpostin work?

Prostaglandin E2 acts on the uterus and cervix, stimulating contractions and softening the cervix (cervical ripening), which prepares the body for natural labor.

3. How is Alpostin Injection administered?

Alpostin is administered intravaginally or intracervically by a trained healthcare professional in a hospital or clinic setting. The dosage depends on the patient’s condition and stage of labor.

4. Who can use Alpostin?

Alpostin is prescribed for pregnant women requiring labor induction under medical supervision. It should only be used in a hospital setting due to the risk of strong uterine contractions.

5. What are the possible side effects of Alpostin Injection?

Some common side effects include:

• Uterine contractions or cramping
• Back pain
• Nausea or vomiting
• Diarrhea
• Fever or chills

Severe side effects may include hyperstimulation of the uterus, fetal distress, or allergic reactions. Immediate medical attention is required in such cases.

6. Who should avoid Alpostin Injection?

Do not use Alpostin if the patient has:

• Previous cesarean section or uterine surgery with risk of rupture
• Active genital herpes or pelvic infection
• Placenta previa or abnormal fetal positioning
• Known allergy to prostaglandins

7. Can Alpostin affect the baby?

Alpostin is used to induce labor under close monitoring. Strong contractions may sometimes cause fetal distress. Continuous fetal monitoring is essential to ensure the safety of both mother and baby.

8. How long does it take for Alpostin to work?

The onset of labor after Alpostin administration varies between patients. Cervical ripening may take several hours, and effective contractions typically begin within 2–6 hours, depending on dosage and individual response.

9. Can Alpostin be used at home?

No. Alpostin must be used in a hospital or clinical setting with continuous monitoring of the mother and baby due to potential risks of strong uterine contractions and fetal complications.

10. How should Alpostin Injection be stored?

Store in a refrigerated place between 2°C and 8°C. Protect from light and do not freeze. Keep out of reach of children and use before the expiration date.