Alpostin Alprostadil Injection

1. What is Alpostin (Alprostadil) Injection used for?

Alpostin contains Alprostadil, a prostaglandin E1 (PGE1) analog. It is commonly used to treat erectile dysfunction (ED) in men and to maintain patent ductus arteriosus (PDA) in newborns with certain congenital heart defects.

2. How does Alprostadil in Alpostin work?

Alprostadil works by relaxing smooth muscles and increasing blood flow to specific areas. In ED, it enhances blood flow to the penis to achieve an erection. In newborns, it helps keep the ductus arteriosus open to improve blood circulation.

3. How is Alpostin Injection administered?

Alpostin is administered by intracavernosal injection for ED or intravenously for PDA under strict medical supervision. The dosage and administration depend on the patient’s condition and response to treatment.

4. Who can use Alpostin Injection?

Alpostin for ED is prescribed for adult men under medical supervision. For PDA, it is used in newborns with congenital heart defects in a hospital setting. Use only under doctor guidance.

5. What are the common side effects of Alpostin Injection?

Common side effects include:

• Pain or redness at the injection site
• Dizziness or lightheadedness
• Flushing or headache
• Prolonged erection (priapism) in ED patients

Seek medical attention immediately if you experience severe pain, prolonged erection over 4 hours, or signs of allergic reaction.

6. Who should avoid using Alpostin Injection?

Avoid Alpostin if you have:

• Allergy to Alprostadil
• Severe cardiovascular conditions or low blood pressure
• Peyronie's disease or penile deformities for ED treatment
• Bleeding disorders

7. Can Alpostin Injection be used during pregnancy or breastfeeding?

Alpostin is generally not used in pregnant or breastfeeding women. Its use is restricted to specific medical conditions in newborns or men, as prescribed by a doctor.

8. Can Alpostin interact with other medications?

Yes, interactions may occur with:

• Blood pressure medications
• Anticoagulants
• Other ED treatments

Always inform your doctor about all medications and supplements you are taking.

9. How long does it take for Alpostin Injection to work?

For ED, an erection usually occurs within 5–20 minutes after injection. For newborns with PDA, the effect of keeping the ductus arteriosus open is immediate but requires continuous monitoring by a healthcare professional.

10. How should Alpostin Injection be stored?

Store the injection in a refrigerated place between 2°C and 8°C. Protect from light and do not freeze. Keep out of reach of children and use before the expiration date.